Integrative approach to ADHD (Integrative Approach)
ADHD has significant nutritional underpinnings including omega-3 deficiency, iron insufficiency, zinc depletion, and magnesium-B6 imbalance. Integrative protocols address these root drivers alongside stimulant medications — often improving efficacy and tolerability.
Evidence highlight
EPA/DHA supplementation (≥750mg EPA/day) improves attention, hyperactivity, and cognitive performance in pediatric ADHD across 16 RCTs — Grade A evidence. Ferritin <30 ng/mL correlates with ADHD symptom severity and is correctable.
Commonly used supplements
- EPA/DHA (high-dose omega-3)
- Zinc picolinate
- Magnesium glycinate + B6
- Iron (if ferritin <30)
- L-theanine
- Phosphatidylserine
- Pycnogenol
- Vitamin D
Key interaction flags
Iron + stimulant medications (iron can reduce amphetamine efficacy — separate timing)
High-dose omega-3 + anticoagulants
Zinc + copper (deplete copper at high doses)
Phosphatidylserine + anticoagulants
Labs to consider
Clinical note
Ferritin levels below 30 ng/mL independently predict ADHD symptom severity — many practitioners use >50 ng/mL as the functional target. Iron repletion alone can meaningfully reduce stimulant dose requirements. Always check iron before adding supplements that may interact with absorption.
Build a complete ADHD (Integrative Approach) protocol with ClarityTX
Describe your patient's case. ClarityTX synthesizes from clinician-reviewed monographs and checks all drug-supplement interactions automatically.
Evidence-graded supplements
Every supplement recommendation for ADHD (Integrative Approach) carries an A-D evidence grade with a link to the source. You see exactly what the evidence shows before you prescribe.
Automatic interaction checking
ClarityTX checks the full ADHD (Integrative Approach) protocol against the patient's medication list. Severity rated: Contraindicated, Avoid, Monitor, or Caution.
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Switch to patient view: plain-language instructions, dosing schedule, and a 7-day meal plan. Export to PDF or share directly. Use de-identified clinical information.
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