Integrative approach to Insulin Resistance
Insulin resistance is a root-cause driver of PMOS (PCOS), type 2 diabetes, NAFLD, and cardiovascular risk. Addressing it early with targeted nutrition, lifestyle, and supplement support can prevent downstream disease progression.
Evidence highlight
HOMA-IR >1.9 is associated with significantly elevated cardiometabolic risk. Myo-inositol (2-4g/day) reduces HOMA-IR by up to 30% in insulin-resistant women — Grade B evidence.
Commonly used supplements
- Berberine
- Myo-inositol
- Magnesium glycinate
- Chromium picolinate
- Alpha lipoic acid
- Vitamin D
- Omega-3s
- Cinnamon bark extract
Key interaction flags
Berberine + any hypoglycemic medication
Alpha lipoic acid + thyroid medications
High-dose chromium + insulin sensitivity medications
Labs to consider
Clinical note
Insulin resistance rarely presents in isolation. Protocols need to account for its intersection with thyroid status, sex hormone balance, and sleep quality — all of which affect insulin sensitivity independently.
Build a complete Insulin Resistance protocol with ClarityTX
Describe your patient's case. ClarityTX synthesizes from clinician-reviewed monographs and checks all drug-supplement interactions automatically.
Evidence-graded supplements
Every supplement recommendation for Insulin Resistance carries an A-D evidence grade with a link to the source. You see exactly what the evidence shows before you prescribe.
Automatic interaction checking
ClarityTX checks the full Insulin Resistance protocol against the patient's medication list. Severity rated: Contraindicated, Avoid, Monitor, or Caution.
Patient-ready in one click
Switch to patient view: plain-language instructions, dosing schedule, and a 7-day meal plan. Export to PDF or share directly. Use de-identified clinical information.
Your first Insulin Resistance protocol is free
No credit card required. Start with a clinical question, review the evidence, and build a full protocol when needed.
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